Ultrastructural changes in uterine myometrium of mice with experimentally-induced adenomyosis |
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| Authors: | T. Mori Y. Ohta H. Nagasawa |
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| Affiliation: | (1) Zoological Institute, Faculty of Science, University of Tokyo, Bunkyo-ku, Tokyo, (Japan);(2) Department of Biology, School of General Education, Tottori University, Koyama, Tottori, (Japan);(3) Experimental Animal Research Laboratory, Meiji University, Tama-ku, Kawasaki, (Japan) |
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| Abstract: | Summary Ectopic pituitary transplantation induced a high incidence of adenomyosis in SHN mice. Early signs of the development of adenomyosis were the penetration of stromal connective tissue into myometrium followed by uterine gland invasion. Associated with these changes, the inner layer of myometrium showed the involution of smooth muscle cells and distended intercellular spacesThis work was supported in part by Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan |
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| Keywords: | Mouse, uterine myometrium uterine myometrium, mouse adenomyosis ectopic pituitary transplantation prolactin |
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