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乳糖化羧甲基壳聚糖季铵盐的合成
引用本文:聂鑫,杨安平,张哓林,张春銮,陈飞雨,周秀红,张本健,许惠聪.乳糖化羧甲基壳聚糖季铵盐的合成[J].佛山科学技术学院学报(自然科学版),2011,29(1):81-84.
作者姓名:聂鑫  杨安平  张哓林  张春銮  陈飞雨  周秀红  张本健  许惠聪
作者单位:佛山科学技术学院,检药系,广东,佛山,528000
基金项目:广东省医学科研基金资助项目,广东省科技计划资助项目
摘    要:目的探讨乳糖化羧甲基壳聚糖季铵盐的合成方法.方法以羧甲基壳聚糖为原料,3-氯-2-羟丙基三甲基氯化铵(CTA)为季铵化试剂,合成羧甲基壳聚糖季铵盐,在此基础上,以乳糖为乳糖化试剂,合成乳糖化羧甲基壳聚糖季铵盐.结果通过红外光谱进行初步确认合成乳糖化羧甲基壳聚糖季铵盐.结论乳糖化羧甲基壳聚糖季铵盐可以合成,方法有待进一步...

关 键 词:羧甲基壳聚糖  乳糖  季铵盐  合成

Synthesis of lactosaminated and quaterniz carboxymethyl chitosan
NIE Xin,YANG An-ping,ZHANG Xiao-lin,ZHANG Chun-luan,CHEN Fei-yu,ZHOU Xiu-hong,ZHANG Ben-jian,XU Hui-cong.Synthesis of lactosaminated and quaterniz carboxymethyl chitosan[J].Journal of Foshan University(Natural Science Edition),2011,29(1):81-84.
Authors:NIE Xin  YANG An-ping  ZHANG Xiao-lin  ZHANG Chun-luan  CHEN Fei-yu  ZHOU Xiu-hong  ZHANG Ben-jian  XU Hui-cong
Institution:NIE Xin,YANG An-ping,ZHANG Xiao-lin,ZHANG Chun-luan,CHEN Fei-yu,ZHOU Xiu-hong,ZHANG Ben-jian,XU Hui-cong (Department of Laboratory Pharmacy,Foshan University,Foshan 528000,China)
Abstract:Objectve To study the synthesizing methods of lactosaminated and quaterniz carboxymethyl chitosan.Methods The carboxymethyl chitosan was used as raw material with the 3-chloro-2- hydroxypropyltrimethylammonium chloride(CTA) as agent of quaterniz and lactose as agent of lactosaminated.Results It is found that lactosaminated and quaterniz carboxymethyl chitosan was synthesized by IR.Conclusion Lactosaminated and quaterniz carboxymethyl chitosan could be synthesized,but the method was expected to be improved.
Keywords:carboxymethyl chitosan  lactosaminated  quaterniz  synthesis  
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