Kinetics of interferon action |
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| Authors: | H Koblet R Wyler U Kohler |
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| Institution: | (1) Present address: Institute of Medical Microbiology, University of Berne, Friedbühlstrasse 51, CH-3008 Berne, (Switzerland);(2) Present address: Institute of Virology, University of Zurich, Winterthurerstrasse 266A, CH-8057 Zurich, (Switzerland) |
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| Abstract: | Summary A kinetic analysis of the action of interferon with different preparations in chick embryo fibroblast cell culture gives additional evidence for interaction of interferon with the cell surface, compatible with the idea that interferon is not taken up by the cells. With certain assumptions the binding constant is in the range of 1013 l/Mol].Work supported by the Swiss National Science Foundation, grants 3.399, 3.1050 and 3.540. |
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