Anti-androgenic action of cyproterone acetate in the epididymis of the rhesus monkey |
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Authors: | T N R V Thampan N Dinakar M R N Prasad |
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Institution: | (1) Department of Zoology, University of Delhi, 110007 Delhi, (India);(2) Present address: Department of Cell Biology, Baylor College of Medicine, 77030 Houston, Texas, USA |
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Abstract: | Summary Cyproterone acetate (1 M) inhibited the binding of labeled testosterone (T) and dihydrotestosterone (DHT) in the caput and cauda epididymides of the rhesus monkey. The same concentration of the anti-androgen failed to inhibit androgen binding in the ductus deferens, prostate and seminal vesicles.The investigation was supported by financial assistance from the Indian Council of Medical Research and the University Grants Commission. CA was a gift from Dr. F. C. Neumann, Scherring AG, Berlin. |
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