不同发育时期小鼠卵巢腔前卵泡的分布及形态学研究

通过石蜡切片-HE染色技术,系统研究小鼠生后不同发育时期即3,5,7,10,15,20,30,45 d卵巢的卵泡分布、形态结构及发育规律.研究结果表明,随着小鼠卵巢的发育,由最初的无皮髓质之分到皮髓明显可见,卵泡从只见聚集呈条索状到发育成原始卵泡、初级卵泡、次级卵泡,直至有腔的形成.从数量上看,原始卵泡逐渐减少,初次级卵泡逐渐增多,有腔卵泡数量也从无到有从少到多.卵巢由最初的无卵泡发育到有许多大小不等、处于不同发育时期的卵泡、大部分有腔样结构.在此发育过程中会伴有卵泡的闭锁.小鼠卵巢中各级腔前卵泡的分布具有区域性.

The Distribution and Morphology of Different Developmental Stages of Mouse Preantral Follicles

In this paper,we investigated follicle distribution,morphological structure and rule of development of ovary at postnatal 3,5,7,10,15,20,30,45 days of ages using by paraffin section-HE staining method. The results showed that with the development of mouse,ovary develops from non-cortex and medulla assigned in the initia to the situation that cortex can be seen apparently. Follicles developed from the streak were gathered so as to develop into primordial follicles,primary follicles,secondary follicles,until cavity formation. Judging from the numbers, primordial follicles decreased in the initial stage follicles gradually,while primary follicles and secondary follicles increased gradually,and the number of antral follicles was from scratch to less than mature follicles relatively. Developing from the initial scratch to many non-sizes at different developmental stages of follicles,the majority of ovarian follicle has cavity-like structure. The distribution of follicles in the ovaries is regional.