The cellular receptor of the alpha-beta interferons |
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| Authors: | K. E. Mogensen G. Uzé P. Eid |
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| Affiliation: | (1) Laboratoire d'Oncologie Virale, CNRS ER 274, 7 rue Guy Môquet, F-94802 Villejuif Cedex, France |
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| Abstract: | Summary This is a selective review of recent trends in research on the cellular receptor for the alpha-beta interferons. It deals mainly with work published in the last three years (1985–88), and therefore mainly with receptors for the human interferons. The binding characteristics of several human alpha interferons are examined, and the importance of in vitro experimental models for establishing the relationship between receptor binding and the cellular response is emphasized. |
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| Keywords: | Interferon receptor polypeptide receptor multiple ligands cellular differentiation binding response relationship |
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