Die Speicherung von Blutproteinen in den Histiozyten nach vorhergehender Histamineinwirkung

Summary By means of their special histological method, the storage of plasma proteins in the histiocytes was studied by the authors in rats and mice. If injected subcutaneously, both homologous and heterologous serum proteins were stored to the same extent at the site of the injection by the histiocytes of the connective tissue.After smearing the skin with histamine or after subcutaneous injection of histamine, intensive storage of protein occurs locally in the histiocytes. Because of the effect of histamine increasing permeability, these cells accumulate in their body the plasma proteins abundantly escaping from the blood stream.Even under physiological conditions, plasma proteins are constantly taken up and destroyed by the reticuloendothelial cells and this function has a fundamental biological importance.