| 左金丸及类方的HPLC指纹图谱研究 |
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| 引用本文： | 邓桂明, 王朝润, 张鹤鸣, 刘颂豪, 杨立平. 左金丸及类方的HPLC指纹图谱研究[J]. 华南师范大学学报（自然科学版）, 2012, 44(2). |
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| 作者姓名： | 邓桂明 王朝润 张鹤鸣 刘颂豪 杨立平 |
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| 作者单位： | 3.2.湖南中医药大学第一附属医院;4.3.华南师范大学国家中医药管理局中医药与光子技术三级实验室;5.4.华南师范大学信息光电子科技学院;6.5.湖南省肿瘤医院 |
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| 基金项目： | 湖南省科技计划项目，湖南省中医药管理局资助项目 |
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| 摘 要： | 建立左金丸及其类方的HPLC指纹图谱.用RP-HPLC法，乙腈(A)-水(B)(含0.06%冰醋酸， 10mmol/L醋酸铵)为流动相，梯度洗脱.并对其相似度比较分析.配伍比例的不同可导致物质基础存在显著差异性.为左金丸及其类方的质量控制提供依据.
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| 关 键 词： | 左金丸 指纹图谱 配伍比例 |
| 收稿时间： | 2011-12-05 |
| 修稿时间： | 2012-02-23 |
The Fingerprint Study of Zuojin Pill and Its Similar Formulaes by HPLC |
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| THE FINGERPRINT STUDY OF ZUOJIN PILL AND ITS SIMILAR FORMULAES BY HPLC[J]. Journal of South China Normal University (Natural Science Edition), 2012, 44(2). |
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| Authors: | DENG Guiming WANG Chaorun ZHANG Heming LIU Songhao YANG Liping |
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| Affiliation: | 1.College of Biophotonics,South China Normal University,Tertiary Laboratory of Chinese Medicine & Photonics State Administration of TCM,Guangzhou 510631,China;2.The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 41007,China;3.Hunan Provincial Tumor Hospital,Changsha 410013,China) |
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| Abstract: | To set up the HPLC fingerprint of Zuojin pill and its similar formulaes.The fingerprint of Zuojin pill and its similar formulaes were determined by RP-HPLC,acetonitrile(A)-water(B)(including 0.06% glacial acetic acid,10mmol/L ammonium acetate) as mobile phase and gradient elution.The similarity was analysed as well.Different compatibility proportion can lead to the significant difference in material foundation and serve as a quality control method for Zuojin pill and its similar formulaes. |
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| Keywords: | Zuojin pill fingerprint HPLC |
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