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左金丸及类方的HPLC指纹图谱研究
引用本文:邓桂明,王朝润,张鹤鸣,刘颂豪,杨立平.左金丸及类方的HPLC指纹图谱研究[J].华南师范大学学报(自然科学版),2012,44(2):80-0.
作者姓名:邓桂明  王朝润  张鹤鸣  刘颂豪  杨立平
作者单位:1.1.1.湖南中医药大学第一附属医院;
基金项目:湖南省科技计划项目,湖南省中医药管理局资助项目
摘    要:建立左金丸及其类方的HPLC指纹图谱.用RP-HPLC法,乙腈(A)-水(B)(含0.06%冰醋酸, 10mmol/L醋酸铵)为流动相,梯度洗脱.并对其相似度比较分析.配伍比例的不同可导致物质基础存在显著差异性.为左金丸及其类方的质量控制提供依据.

关 键 词:左金丸    指纹图谱    配伍比例
收稿时间:2011-12-05

The Fingerprint Study of Zuojin Pill and Its Similar Formulaes by HPLC
DENG Guiming , WANG Chaorun , ZHANG Heming , LIU Songhao , YANG Liping.The Fingerprint Study of Zuojin Pill and Its Similar Formulaes by HPLC[J].Journal of South China Normal University(Natural Science Edition),2012,44(2):80-0.
Authors:DENG Guiming  WANG Chaorun  ZHANG Heming  LIU Songhao  YANG Liping
Institution:1.College of Biophotonics,South China Normal University,Tertiary Laboratory of Chinese Medicine & Photonics State Administration of TCM,Guangzhou 510631,China;2.The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 41007,China;3.Hunan Provincial Tumor Hospital,Changsha 410013,China)
Abstract:To set up the HPLC fingerprint of Zuojin pill and its similar formulaes.The fingerprint of Zuojin pill and its similar formulaes were determined by RP-HPLC,acetonitrile(A)-water(B)(including 0.06% glacial acetic acid,10mmol/L ammonium acetate) as mobile phase and gradient elution.The similarity was analysed as well.Different compatibility proportion can lead to the significant difference in material foundation and serve as a quality control method for Zuojin pill and its similar formulaes.
Keywords:Zuojin pill  fingerprint  HPLC
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