Structural alterations in normal and axotomized facial nucleus neurons after treatment with morphine

Summary Chronic morphine administration induced ultrastructural alterations in neurons of the facial nucleus and increased the incidence of cell death after axotomy. These findings may correlate with the significant depression of neuronal metabolism known to occur after opiate treatment.Supported by a grant from the United States Public Health Service, NIDA 5 RO1 DA 0014-06.