Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats |
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| Authors: | Y Nakabou K Ikeuchi H Minami H Hagihira |
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| Institution: | (1) Department of Nutrition, School of Medicine, The University of Tokushima, 770 Tokushima, (Japan) |
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| Abstract: | Summary The sucrase activity in enterocytes isolated from the villus crypt axis was found to increase in all regions of the villus from day 2 after induction of diabetes, and the increase continued until day 4. In contrast, alkaline phosphatase activity increased mainly in the apical one-third of the villus-crypt column, and the increase occurred abruptly on day 4 with increase in food intake. |
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| Keywords: | Rat alloxan diabetes intestinal villus alkaline phosphatase sucrase epithelial cells villus-crypt axis |
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