Prednisolone-binding proteins in the rat liver and gastrocnemius muscle

Summary Quantitatively, liver cytosol preparations were found to contain 2.3 times the number of prednisolone-binding proteins that were present per mg total protein in the rat gastrocnemius muscle. The liver proteins were larger molecules and, in a low ionic environment, were more chemically stable than the muscle proteins.The authors gratefully acknowledge the advice and encouragement of Dr G.A.J. Goodlad.