| 糖尿病患者红细胞膜流动性及其影响因素的探讨 |
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| 引用本文： | 刘国宁,吴凤兰,张亚非.糖尿病患者红细胞膜流动性及其影响因素的探讨[J].暨南大学学报,2000,21(2):37-39. |
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| 作者姓名： | 刘国宁 吴凤兰 张亚非 |
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| 作者单位： | [1]暨南大学医学院卫生学教研室 [2]营养学教研室 |
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| 摘 要： | 探讨糖尿病患者红细胞膜流动性及其影响因素，方法对４３例受试者的红细胞膜流动性，脂质过氧化物终产物丙二醛、血清胆固醇、血清甘油三脂和维生素Ｅ进行测定分析。结果：糖尿病组与健康对照组比较，前者是红细胞膜流动性和血清ＶＥ含量显著降低（ｔ＝５．４５３、２．３３９，Ｐ〈０．０１）；血浆丙二醛、血清胆固醇、甘油三脂含量升高，两者比较有显著性差异（ｔ＝３．０２６、２．３８２、２．９６５，Ｐ〈０．０５）。结论：糖
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| 关 键 词： | 糖尿病 膜流动性 影响因素 红细胞膜 生化指标 |
| 文章编号： | 1000－9965(2000)02－0037－03 |
| 修稿时间： | 1999－09－10 |
Study of the membranous fluidity of red cells
and the effected elements of the diabetes patients |
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| LIU Guo- ning
WU Fen- lan
,ZHANG Ya - fei
,ZHANG Ming- zhu
WANG Sheng- yong.Study of the membranous fluidity of red cells
and the effected elements of the diabetes patients[J].Journal of Jinan University(Natural Science & Medicine Edition),2000,21(2):37-39. |
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| Authors: | LIU Guo- ning
WU Fen- lan ZHANG Ya - fei ZHANG Ming- zhu
WANG Sheng- yong |
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| Institution: | LIU Guo- ning
;(Dept. Of Public Health Guangzhou 510632, China);WU Fen- lan
,ZHANG Ya - fei
,ZHANG Ming- zhu
;( Dept. Of Nutritional Guangzhou 510632, China);WANG Sheng- yong
;( Dept. Of Epidemiology of JNUMC Guangzhou 510632, China) |
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| Abstract: | Aim: To study the membranous fluidity of the red cells and the effected elements of tile di- abetes patients. Methods:43 patients were given tests and analysis on membranous fluidity of red cells and the end product (Malonyldial dehyde MDA) of peroxidation. serum cholestrol(CHO), serum triglyceride (TG), and Vitamin E(VE). Results: Results showed that as against the contrast group (healthy subjects) diabetec patients showed a remarkable decrease of red cell membranous fluidity (t = 5. 453, P < 0.01 ), and serum VE content(t = 2. 339, P < 0. 01 ); and an increase of serum MDA. CHO. TG(t = 3. 026, 2. 382, 2. 965, P < 0. 01 ). Conclusion: The decrease of diabetes patients membranous fluidity of red cell has close relations with the lipid peroxidation and the change of lipid composition and anti - peroxidation. Therefore, in the conrse of improving the state of hyperglycemia and hyperlipemia, promoting the anti - peroxidation of diabetes patients is of great significance to remedying red cell trauma, improving the red cell membranous fluidity, and preventing micr - ovascular complications. |
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| Keywords: | diabetes mcllitus membrane fluidity effected elements |
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