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Three-dimensional reconstruction of mature dengue virus cultured in neutral medium
作者姓名:LIKunpeng  LIYinyin  LIJing  WEIwei  FANGMeiyu  LIUJianwei
作者单位:[1]SchoolofLifeScience,SunYat-SenUniversity,Guangzhou510275,China [2]MilitaryMedicalInstitute,GuangzhouCommandPLA,Guangzhou510507,China
摘    要:Dengue virus (DEN), a single positively stranded RNA virus, is a family member of Flaviviridae; it uses the mosquito Aeodes aegypti as its principle vector to cause what is known as Dengue fever. Its genome is -10.8-kb in size and has one open reading frame encoding three structural proteins: capsid (C), precursor of the membrane (prM) and envelope (E), as well as seven non-structural proteins from a single polypeptide. The immature DEN particles are assembled on the inner surface of the endoplasmic reticulum(ER) and budded into the lumen of the ER.

关 键 词:三维空间重建  登革热病毒  中性媒介  蚊子  传播途径
收稿时间:2005-03-03

Three-dimensional reconstruction of mature dengue virus cultured in neutral medium
LIKunpeng LIYinyin LIJing WEIwei FANGMeiyu LIUJianwei.Three-dimensional reconstruction of mature dengue virus cultured in neutral medium[J].Chinese Science Bulletin,2005,50(12):1276-1278.
Authors:Kunpeng Li  Yinyin Li  Jing Li  Wei Wei  Meiyu Fang  Jianwei Liu
Institution:LI Kunpeng1*, LI Yinyin1*, LI Jing1, WEI wei1, FANG Meiyu2 & LIU Jianwei2 1. School of Life Science, Sun Yat-Sen University, Guangzhou 510275, China; 2. Military Medical Institute, Guangzhou Command PLA, Guangzhou 510507, China
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