| Bioinformatic Analysis of Putative Gene Products Encoded in SARS—HCoV Genome |
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| 引用本文： | 赵心刚,韩敬东,宁元亨,孟安明,陈晔光. Bioinformatic Analysis of Putative Gene Products Encoded in SARS—HCoV Genome[J]. 清华大学学报, 2003, 8(4): 389-394 |
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| 作者姓名： | 赵心刚 韩敬东 宁元亨 孟安明 陈晔光 |
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| 作者单位： | [1]Theseauthorscontributedequallytothiswork. [2]DanaFarberCancerInstitute,HarvardUniversity,Boston,MA02115,USA [3]StateKeyLaboratoryofBiomembraneandMembraneBiotechnology,DepartmentofBiologicalSciencesandBiotechnology,TsinghuaUniversity,Beijing100084,China [4]Towhomcorrespondenceshouldbeaddressed.,DepartmentofBiologicalSciencesandBiotechnology,TsinghuaUniversity,Beijing100084,China |
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| 基金项目： | Supported by the Anti- SARS Fund of Tsinghua University，the National Science Foundation forOutstanding Young Scientist of China (No.30 12 5 0 2 1)，and the Bugher Foundation(New York) |
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| 摘 要： | The cause of severe acute respiratory syndrome (SARS) has been identified as a new coronavirus named as SARS-HCoV. Using bioinformatic methods, we have performed a detailed domain search. In addition to the viral structure proteins, we have found that several putative polypeptides share sequence similarity to known domains or proteins. This study may provide a basis for future studies on the infection and replication process of this notorious virus.
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| 关 键 词： | 生物信息学 SARS－HCoV SARS病毒 基因组 基因编码 |
Bioinformatic Analysis of Putative Gene Products Encoded in SARS-HCoV Genome |
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| Affiliation: | State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China;Dana Farber Cancer Institute, Harvard University, Boston, MA 02115, USA |
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| Abstract: | The cause of severe acute respiratory syndrome (SARS) has been identified as a new coronavirus named as SARS HCoV. Using bioinformatic methods, we have performed a detailed domain search. In addition to the viral structure proteins, we have found that several putative polypeptides share sequence similarity to known domains or proteins. This study may provide a basis for future studies on the infection and replication process of this notorious virus. |
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| Keywords: | severe acute respiratory syndrome (SARS) human coronavirus bioinfomatics genome analysis |
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