Pyrolysis of cannabidiol. Structure elucidation of a major pyrolytic conversion product

Summary Pyrolysis of cannabidiol, one of the major constituents of Cannabis sativa, yields a mixture of components. Next to previously identified products, a major conversion product has now been isolated and identified. The unusual and stereospecific route of formation of this compound with altered chromophore is discussed.Acknowledgments. This research was supported by the Dutch Department of Public Health and Environmental Hygienics. Thanks are due to R. D. van Ooyen who provided technical assistance, Dr M. J. A. de Bie and Dr W. Heerma for valuable discussions, Drs J. W. Marsman and Ir T. Spoormaker for performing PMR experiments.