| Multiple conformations of proteins in native state |
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| 引用本文： | SHENG Xiangrong,PAN Xianming. Multiple conformations of proteins in native state[J]. 自然科学进展(英文版), 2002, 12(3): 161-165 |
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| 作者姓名： | SHENG Xiangrong PAN Xianming |
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| 作者单位： | National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China,National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China |
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| 基金项目： | Supported by the National Natural Science Foundation of China (Grant No. 30000029) and the Major State Basic Research Development Program of China (G199075606) |
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| 摘 要： | Examples of protein sequences that can adopt multiple native states are recently accumulated. Characterization of the protein multiple conformations will have important implications for our understanding of the relationship between structure and function, and their folding kinetics. In present review, the experimental evidence for the existence of multiple conformations in the native state of proteins, the molecular basis and the biological significance of multiple conformations of proteins are focused.
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| 关 键 词： | protein folding multiple native conformations molecular basis biological significance |
Multiple conformations of proteins in native state |
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| SHENG Xiangrong,PAN Xianming. Multiple conformations of proteins in native state[J]. Progress in Natural Science, 2002, 12(3): 161-165 |
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| Authors: | SHENG Xiangrong PAN Xianming |
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| Affiliation: | National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China |
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| Abstract: | Examples of protein sequences that can adopt multiple native states are recently accumulated. Characterization of the protein multiple conformations will have important implications for our understanding of the relationship between structure and function, and their folding kinetics. In present review, the experimental evidence for the existence of multiple conformations in the native state of proteins, the molecular basis and the biological significance of multiple conformations of proteins are focused. |
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| Keywords: | protein folding multiple native conformations molecular basis biological significance |
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