Dantrolene and the effect of temperature on the spontaneous release of transmitter at the frog neuromuscular junction |
| |
| Authors: | S. J. Publicover C. J. Duncan |
| |
| Affiliation: | (1) Department of Zoology, University of Liverpool, P. O. Box 147, L69 3BX Liverpool, (England);(2) Present address: Department of Zoology and Comparative Physiology, University of Birmingham, P. O. Box 363, B 15 2TT Birmingham, (England) |
| |
| Abstract: | Summary The characteristic effect of temperature on m.e.p.p. frequency at the amphibian neuromuscular junction is unaltered by the presence of Dantrolene (an agent that is believed to reduce the efflux of Ca2+ from intracellular stores) or by changes in [Ca2+]o. It is concluded that temperature affects the release system directly, with a transition temperature at about 16°C. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
