Quercetin interacts with calmodulin,a calcium regulatory protein |
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Authors: | H Nishino E Naitoh A Iwashima K Umezawa |
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Institution: | (1) Departments of Biochemistry and Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, 602 Kyoto, (Japan);(2) Department of Molecular Oncology, Institute of Medical Science, University of Tokyo, Minato-ku, 108 Tokyo, (Japan) |
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Abstract: | Summary Quercetin was found to interact with the Ca2+-calmodulin complex, suggesting that it may act as a calmodulin antagonist in vivo to inhibit calmodulin-dependent phenomena caused by biologically active agents, including tumor promoters.This work was supported in part by grants-in-aid for scientific research from the Ministry of Education, Science and Culture, Japan. |
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