非洛地平缓释片治疗老年高血压病临床疗效观察

目的：观察非洛地平缓释片治疗老年高血压病的临床疗效．方法：选择在我院住院治疗的老年原发性高血压病人216例，每日早餐口服非洛地平缓释片2．5mg，采用逐渐增量的方法，最大剂量为10mg／d，疗程为6w．对比用药前后心电图、实验室检查等各项指标的变化，采用自身对照方法动态观察老年高血压病人服用非洛地平缓释片后血压的变化情况．结果：治疗前后心电图、实验室检查等无明显变化，心率虽有所加快，但无统计学差异，非洛地平缓释片治疗后有效病例共208例，每日剂量在7．5mg以下者占78．48％，平均剂量为5．25mg，不良反应发生率7．87％．结论：非洛地平缓释片是一种安全、有效的降压药，可以提供临床应用，推荐的常用剂量为5mg／d，早晨餐后一次服，最大剂量可用到10mg／d．

The Observation on Clinical Effects of Felodipine Sustained-release Tablets Treating Senile Essential Hypertension

Objective:To observe the clinical effects of Felodipine Sustained - release Tablets treating senile essential hypertension. Methods: 216 senile patients with essential hypertension who were treated in our hospital were chosen to be observed. They took 2. 5mg Felodipine Sustained -release Tablets after breakfast and the dose was increased gradually. The max dose was 10mg/d. The treatment course is 6 weeks. The ECG and the indexes of laboratory examination were compared before and after taking the medicine. The changes of blood pressure of senile patients with essential hypertension were observed dynamically after taking the medicine through the auto -control method. Results: The ECG and the indexes of laboratory examination didn't change very apparently after the treatment. The heart rate was raised but there was no statistical difference. The effective cases treated with Felodipine Sustained - release Tablets were 208(78.48%). The patients took 7.5mg/d, the average dose 5.25mg/d,and the untoward reaction rate was 7.87% . Conclusion: Felodipine Sustained- release Tablets is an effective and safe hypotensor. It can be recommended and be used clinically. The routine dose is 5mg/d and it should be taken after breakfast. The max dose can get to 10mg/d.