Magnetic resonance and the human brain: anatomy, function and metabolism |
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Authors: | I -F Talos A Z Mian K H Zou L Hsu D Goldberg-Zimring S Haker J G Bhagwat R V Mulkern |
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Institution: | (1) Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA;(2) Department of Radiology, Boston University, Boston, Massachusetts, USA;(3) Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA;(4) Department of Radiology, Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA |
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Abstract: | The introduction and development, over the last three decades, of magnetic resonance (MR) imaging and MR spectroscopy technology
for in vivo studies of the human brain represents a truly remarkable achievement, with enormous scientific and clinical ramifications.
These effectively non-invasive techniques allow for studies of the anatomy, the function and the metabolism of the living
human brain. They have allowed for new understandings of how the healthy brain works and have provided insights into the mechanisms
underlying multiple disease processes which affect the brain. Different MR techniques have been developed for studying anatomy,
function and metabolism. The primary focus of this review is to describe these different methodologies and to briefly review
how they are being employed to more fully appreciate the intricacies associated with the organ, which most distinctly differentiates
the human species from the other animal forms on earth.
Received 1 November 2005; received after revision 11 January 2006; accepted 25 January 2006 |
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Keywords: | Magnetic resonance imaging (MRI) magnetic resonance spectroscopy (MRS) brain anatomy function metabolism |
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