| CTX对家兔肺损伤早期血气与酸碱平衡调节改变的研究 |
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| 引用本文： | 符健,邝少轶,邢桂兰,邢增术.CTX对家兔肺损伤早期血气与酸碱平衡调节改变的研究[J].海南大学学报(自然科学版),2004,22(1):75-77. |
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| 作者姓名： | 符健 邝少轶 邢桂兰 邢增术 |
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| 作者单位： | 海南医学院,药理学教研室,海南,海口,571101;海南医学院,药理学教研室,海南,海口,571101;海南医学院,药理学教研室,海南,海口,571101;海南医学院,药理学教研室,海南,海口,571101 |
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| 基金项目： | 海南省自然科学基金资助项目(39305) |
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| 摘 要： | 应用油酸、肾上腺素型肺损伤模型观察家兔早期血气变化,并与CTX组进行对照比较.结果表明:家兔注射CTX、油酸和肾上腺素后3h,呼吸呈进行性加快,PaO2和O2SAT下降,PaCO2、ctCO2、HCO3—降低.CTX引起血气中各项指标改变是肺急性损伤所致,与油酸、肾上腺素型肺损伤相似.
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| 关 键 词： | 眼镜蛇心脏毒素 油酸 肾上腺素 家兔 肺损伤 血气分析 |
| 文章编号： | 1004-1729(2004)01-0075-03 |
| 修稿时间： | 2003年11月6日 |
Study on Early Changes of Blood Gas and Acid-Base Regulation in Modes of Rabbits'Lung Injury Caused by Cardiotoxin |
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| FU Jian,KUANG Shao-yi,XING Gui-lan,XING Zeng-shu.Study on Early Changes of Blood Gas and Acid-Base Regulation in Modes of Rabbits'Lung Injury Caused by Cardiotoxin[J].Natural Science Journal of Hainan University,2004,22(1):75-77. |
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| Authors: | FU Jian KUANG Shao-yi XING Gui-lan XING Zeng-shu |
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| Abstract: | To investigate the animal lung injury caused by cardiotoxin(CTX) of cobra. Early changes of blood gas in the modes of rabbits' lungs injury caused by oleic acid and adrenaline were observed,comparing with the group of those caused by cardiotoxin(CTX). The results showed that CTX was injected, after 3 hours,the respiration of rabbits increasingly accelerated,PaO_2 and O_2SAT reduced,PaCO_2 and ctCO_2 decreased,and the concentration of HCO~-_3 reduced. The changes caused by CTX in the indexes of blood gas are the results of acute lung injury,which are similar to the modes of lung injury caused by oleic acid and adrenaline. |
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| Keywords: | cardiotoxin of cobra oleic acid adrenaline rabbit lung injury blood gas analysis |
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