Effect of nerve stimulation on rat skeletal muscle. A study of plasma membrane |
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Authors: | A Shah F Nagao V Sahgal H Singh |
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Institution: | (1) Neuromuscular Studies Unit, Rehabilitation Institute of Chicago, 345 E. Superior Street, 60611 Chicago, Illinois, USA |
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Abstract: | Summary The gastrocnemius muscle of the rat showed no morphological, histometric or plasma membrane changes, after sciatic nerve stimulation with a 5 mA current for 30 to 60 min, 10 mA for 30 min and 15 mA for 5 min. However, 10 mA for 60 and 200 min gave rise to mitochondrial and plasma membrane abnormalities. These changes were absent after a rest period. The results indicated the sciatic nerve stimulation at 10 mA for 60 and 200 min caused reversible changes in the rat skeletal muscle mitochondria and plasma membrane. |
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Keywords: | Electrical stimulation membrane morphometry muscle ultrastructure |
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