Fine structures of the basophil infiltration in regional lymph nodes of the guinea-pig after the intradermal injection of T cell mitogens |
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Authors: | M Kimura K Takaya |
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Institution: | (1) Department of Anatomy, Toyama Medical and Pharmaceutical University, Faculty of Medicine, 2630 Sugitani, 930-01 Toyama, (Japan) |
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Abstract: | Summary Basophil-rich infiltrates in regional lymph nodes of guinea-pigs were demonstrated by electron microscopy after the intradermal
injection of T cell mitogens (PHA and Con A). Basophils infiltrated the stroma of the lymph node via the postcapillary venules
(PCV) and migrated to the paracortex. Prior to infiltration of the lymph nodes a cutaneous basophil hypersensitivity reaction
was seen in the mitogen-injected skin. B cell mitogen (LPS) injection did not induce this response. |
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Keywords: | |
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