| 羟基磷灰石涂层的骨结合行为 |
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| 引用本文： | 毛大立,曹海萍,常程康,顾云峰.羟基磷灰石涂层的骨结合行为[J].上海交通大学学报,2003,37(2):264-268. |
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| 作者姓名： | 毛大立 曹海萍 常程康 顾云峰 |
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| 作者单位： | 1. 上海交通大学,材料科学与工程学院,上海,200030
2. 同济大学附属同济医院,口腔科,上海,200065 |
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| 基金项目： | 上海市青年科技启明星计划项目 ( 98Q E1 40 31 ) |
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| 摘 要： | 使用等离子喷涂技术，在钛合金表面制备了羟基磷灰石涂层。采用动物实验的方法，研究羟基磷灰石涂层的生物相容性。生物力学实验结果表明，使用羟基磷灰石涂层，可以显著提高骨组织与种植体的界面结合强度。扫描电镜观察显示，羟基磷灰石涂层与骨组织形成骨性结合，而钛合金种植体与骨组织之间存在纤维组织结构。两种不同的界面结构，是导致种植体与骨组织结构强度差异的主要原因。
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| 关 键 词： | 等离子喷涂 羟基磷灰石涂层 生物活性 动物实验 |
| 文章编号： | 1006-2467(2003)02-0264-05 |
| 修稿时间： | 2001年10月24 |
Investigation on the Bonding Behavior of Hydroxyapatite Coating to Hard Tissue |
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| MAO Da li ,CAO Hai ping ,CHANG Cheng kang ,GU Yun feng.Investigation on the Bonding Behavior of Hydroxyapatite Coating to Hard Tissue[J].Journal of Shanghai Jiaotong University,2003,37(2):264-268. |
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| Authors: | MAO Da li CAO Hai ping CHANG Cheng kang GU Yun feng |
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| Institution: | MAO Da li 1,CAO Hai ping 2,CHANG Cheng kang 1,GU Yun feng 2 |
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| Abstract: | Hydroxyapatite coating was applied to the surface of titanium alloy employing plasma spray technology. An animal model was employed to investigate the biocompatibility of the hydroxyapatite coating. It was revealed by push out test that the hydroxyapatite coating greatly prompt the bonding strength between implant and surrounding hard tissues. SEM observation shows that a biological fixation is created between bone and hydroxyapatite, while a layer of fiber is formed between non coated titanium implant and surrounding bone. The different interfacial fixation is the main factor, which causes great difference in interfacial strength. |
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| Keywords: | plasma spray hydroxyapatite coating bioactivity animal model |
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