Thiaminpyrophosphatase bei der experimentellen Diphtherieintoxikation |
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| Authors: | S Witkowski B Filipowicz |
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| Institution: | (1) Institut für allgemeine und physiologische Chemie der Medizinischen Akademie Lódz, Polen |
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| Abstract: | Summary The determinations of thiamine pyrophosphatase activity were carried out in the liver homogenates of normal guinea-pigs and those poisoned with diphtheria toxin.The enzyme activity in the toxaemic liver tissue is twice that of normal guinea-pigs. It is supposed that this result may partly explain the increased level of pyruvic acid in the blood of patients with diphtheria. Further studies on this problem are under way. |
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