RFLP analysis of nov gene in tumor and normal cells |
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| Authors: | Zeng Xianchun Jiang Dahe Li Wenxin Mao Xin Liu Hui Bernard Perbal |
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| Institution: | (1) College of Life Sciences, Wuhan University, 430072 Wuhan, China;(2) Laboratoire d'Oncologie Virale et Moleculaire, Institut Curie, 91405 Orsay, France |
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| Abstract: | Using human nov (nephroblastoma-overexpressed, nov) DNA as probe, hybridization to total cellular DNAs of tumor and normal
cells digested by restriction enzymes BamHI or EcoRI respectively was carried out through Southern blot. It was observed that
nov gene in these cells is not only highly conserved, but also certains RFLP characteristic. The correlation between RFLP
characteristic of nov gene and its function was analyzed.
Supported by the Natural Science Fundation of China and Doctor Station Foundation
Zeng Xianchun: born in June, 1966, Ph. D. graduate student |
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| Keywords: | nov gene Southern blot restriction fragment length polymorphism |
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