Lowering of liver acetaldehyde but not ethanol concentrations by pretreatment with taurine in ehtanol-loaded rats |
| |
| Authors: | A Watanabe N Hobara H Nagashima |
| |
| Institution: | (1) The First Department of Internal Medicine, Okayama University Medical School, 5-1, 2-chome, Shikata-cho, 700 Okayama, (Japan) |
| |
| Abstract: | Summary A rise in blood and liver acetaldehyde concentrations following ethanol loading (1.5 g/kg b.wt) was significantly reduced when rats were pretreated orally with taurine (0.5 g/kg), a potent in vitro activator of yeast aldehyde dehydrogenase. This taurine pretreatment produced a 4-fold increase in liver taurine content. |
| |
| Keywords: | Taurine acetaldehyde ethanol ALDH |
| 本文献已被 SpringerLink 等数据库收录！ |
