Inducing effect of clofibrate on alkaline phosphatase and histidine-glyoxylate aminotransferase in rat liver |
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Authors: | L. F. Panchenko S. V. Popova V. D. Antonenkov |
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Affiliation: | (1) Department of Biochemistry, All-Union Research Institute of Psychiatry, Kropotkinsky per. 23, 119034 Moscow, (USSR) |
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Abstract: | Summary The activity of plasma membrane alkaline phosphatase and both mitochondrial and peroxisomal histidineglyoxylate aminotransferase was significantly increased in the livers of male rats following treatment with the hypolipidemic drug clofibrate. Cycloheximide or puromycin administration to rats inhibited the effects of clofibrate. |
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