微创外科与动物实验伦理

在动物实验中经常需要外科操作,这些操作必然会对动物的正常组织结构、生理功能产生影响,波及其它非靶器官造成非目的效应,如炎性反应、出血、创伤、疼痛等,这些反应既会干扰动物实验结果,同时也引起动物伦理问题。微创外科是当今医学领域发展最快的学科方向之一,采用微创技术大大地降低了外科操作的创伤反应。本文简要介绍微创医学的新进展,以期促进该技术在动物实验研究中的应用,推动动物实验福利伦理问题的改善。

Minimaly Invasive Surgery and the Ethics of Animal Experimentation

Many animal experiments need surgical technics,which could influence animal’s tissue structure and function,and induce pathophysiology changes interfering the research aim,such as inflamation,hemorrhage,injury and pain,etc.These changes not only interfere the research results,but also cause ethics issues.Minimaly invasive surgery is one of the most rapidly innovated trend in biomedical fields.It markedly reduces the side effects of surgery.This article reviews the development of the minimaly invasive surgery,hope to promote its use in animal experiment,and improve the ethics issues.