Influences of the submaxillary gland of male mice on the immune response to sheep red blood cells |
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Authors: | K Hatakeyama M Hiramatsu N Minami |
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Institution: | (1) Department of Dental Pharmacology, Josai Dental University, 350-02 Saitama, (Japan) |
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Abstract: | Summary Removal of the submaxillary gland (SMG) from male but not female mice caused a suppressed immune response to sheep red blood cells. Administration of a SMG saline extract from male mice to SMG-ectomized males restored the suppressed response to control levels. This suggests that the male mouse SMG contains a factor(s), possibly of an endocrine nature, capable of influencing cells involved in an immune response. |
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