| A large scale screen for genes （3rd chromosome） related to Wingless signaling pathway |
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| 作者姓名： | Lin XD Lin XH Chen JA |
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| 作者单位： | [1]InstituteofAppliedEntomology,ZhejiangUniversity,Hangzhou310029,China [2]DivisionofDevelopmentalBiology,CincinnatiChildren＇sHospitalMedicalCenter,UniversityofCincinnati,Cincinnati,OH45229,USA [3]DivisionofDevelopmentalBiology,CincinnatiChildren＇sHospitalMedicalCenter,UniversityofCincinnati,Cincinnati,OH45229,USA |
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| 摘 要： | A wing specific F 1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.
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| 关 键 词： | 等位基因 染色体 果蝇 基因突变 |
A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway |
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| Lin XD,Lin XH,Chen JA.A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway[J].Journal of Zhejiang University Science,2004,5(2):186-192. |
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| Authors: | Lin Xin-da Lin Xin-hua Chen Jia-an |
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| Institution: | Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China. linxinda@yahoo.com |
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| Abstract: | A wing specific F1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped. |
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