Glucocorticoid localization by radioautography in the rabbit eye following systemic administration of3H-dexamethasone |
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| Authors: | A. N. Tchernitchin Nina Tchernitchin |
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| Affiliation: | (1) Laboratory of Experimental Endocrinology, Department of Experimental Morphology, University of Chile Medical School, Casilla 21104, Correo 21, Santiago, (Chile);(2) Department of Anatomy, Ophthalmology and Medicine, New York Medical College, 10595 Valhalla, N.Y., USA |
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| Abstract: | Summary Dexamethasone was localized radioautographically in the nuclei of target cells of the rabbit eye, following i.v. administration of the labeled steroid. Nuclear receptors in stromal and endothelial cells of the outflow pathway region suggest that glucocorticoids may alter the outflow facility by specific responses of target cells.Acknowledgments. This work was supported by grant EY-01313 of the National Eye Institute, National Institutes of Health, Bethesda, Md, USA. |
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