Effect of continuous illumination on secretion of pregnane compounds by the rat ovary |
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| Authors: | T Kosaka T Sawada S Ichikawa |
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| Institution: | Department of Animal Reproduction, College of Agriculture, University of Osaka Prefecture, Japan. |
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| Abstract: | Differences in the secretion of pregnane compounds from rats with follicular polycystic ovaries under constant light and with normal preovulatory ovaries under light-dark conditions were compared. The injection of LH greatly increased the secretion of progesterone. 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in both types of ovaries, but the response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5 alpha-reductase activity. |
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