| D－胺基半乳糖（D－galactosamine）对小白鼠肝脏的损害作用 |
| |
| 引用本文： | 邵伟,王蕴玲,赵长荣.D－胺基半乳糖（D－galactosamine）对小白鼠肝脏的损害作用[J].天津师范大学学报(自然科学版),1994(2). |
| |
| 作者姓名： | 邵伟 王蕴玲 赵长荣 |
| |
| 作者单位： | 天津师范大学生物系 |
| |
| 摘 要： | 给小鼠一次性腹注Ｄ－胺基半乳糖（Ｄ－Ｇａｌｎ）６００和１２００ｍｇ／ｋｇ，或１６小时内连续６次腹注３００ｍｇ／ｋｇ，停药后４８小时，血清谷丙转氨酶（ＳＧＰＴ）明显升高，局部肝细胞呈现肝炎病理形态改变。病变机理是过量Ｄ－Ｇａｌｎ入肝代替了尿苷二磷酸葡萄糖的代谢途径所引起的。
|
| 关 键 词： | D－胺基半乳糖，肝细胞病变，损肝机理，血清谷丙转氨酶 |
DAMAGE EFFECT OF D-GALACTOSAMINE ON THE MOUSE LIVER |
| |
| ShaoWei,Wang Yunling,Zhao Changyong.DAMAGE EFFECT OF D-GALACTOSAMINE ON THE MOUSE LIVER[J].Journal of Tianjin Normal University(Natural Science Edition),1994(2). |
| |
| Authors: | ShaoWei Wang Yunling Zhao Changyong |
| |
| Abstract: | The mice injected D-galactosamine(D-Galn) ince 600 and 1200 mg per kiro of body weight in adominal cavity,or it should be injected once 300mg and continuous 6 time in 16 hours.After 48 hours showed notable elevation of SGPT.local cells of liver induced pathomorphological change with hepatitis.Pathogenesis were due to D-Galn substitute for uridine diphosphoglucose(UDPG) way of metabolism. |
| |
| Keywords: | D-galactosamine Hepatodegeneration Liver injuries mechanism SGPT |
| 本文献已被 CNKI 等数据库收录！ |
