Comparative analysis of phospholamban phosphorylation in crude membranes of vertebrate hearts |
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| Authors: | H Will I Küttner C Kemsies R Vetter E Schubert |
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| Institution: | (1) Central Institute of Heart and Circulation Research, GDR Academy of Sciences, R.-Rössle-Strasse 10, DDR-1115 Berlin-Buch, (German Democratic Republic) |
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| Abstract: | Summary Phospholamban, a sarcoplasmic reticulum phosphoprotein, is present in the hearts of mammalian, avian, amphibian, and fish species. Phylogenetic changes are indicated by marked differences among species in cardiac phospholamban content and by the absence of Ca2+/calmodulin-dependent phospholamban phosphorylation at an early developmental stage. |
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| Keywords: | Cardiac muscle phylogenesis sarcoplasmic reticulum phospholamban protein kinase Ca2+-transport |
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