| 电针对大脑中动脉阻塞大鼠一氧化氮合酶mRNA表达的影响 |
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| 引用本文： | 金竹青,程介士.电针对大脑中动脉阻塞大鼠一氧化氮合酶mRNA表达的影响[J].暨南大学学报,1998,19(6):120-120. |
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| 作者姓名： | 金竹青 程介士 |
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| 作者单位： | 广东省中医院(金竹青)，上海医科大学神经生物学教研室(程介士) |
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| 摘 要： | 本课题旨在探讨电针对动物急性脑缺血时神经保护作用的可能机制，由于ＮＯ的作用在脑缺血不同阶段及细胞来源而有所不同，因此，观察了电针对脑缺血后各型ＮＯＳｍＲＮＡ表达的影响，结果表明，针刺可能通过抑制脑缺血后ｎＮＯＳｍＲＮＡ，ｉＮＯＳｍＲＡＮ的过量表达而起到对神经元的保护作用
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| 关 键 词： | 大脑中动脉阻塞 电针 RT－RCR法 一氧化氮合酶 mRNA表达 |
Effect of Electro-Acupuncture on Nitric Oxide Synthase Expression in Rat Brain after Middle Cerebral Artery Occlusion |
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| Jin Zhuqing,\,Cheng Jieshi.Effect of Electro-Acupuncture on Nitric Oxide Synthase Expression in Rat Brain after Middle Cerebral Artery Occlusion[J].Journal of Jinan University(Natural Science & Medicine Edition),1998,19(6):120-120. |
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| Authors: | Jin Zhuqing \ Cheng Jieshi |
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| Institution: | Jin Zhuqing 1\ Cheng Jieshi 2 |
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| Abstract: | The possible role of electro-acupuncture in preventing the cerebrale lesion from aute ischemia was investgated. Since the effect of NO is dependent on different stages of celebral ischemia and cellular source.Using semi-quantitative RT-PCR, we studied the expression of different types of NOSmRNA and the effect of electro-acupuncture (EA) in rats with transient cerebral middle artery occlusion (MCAO).The results demonstrated the neuroprotective EA effect might be related to inhibition of nNOS mRNA and iNOSmRAN over-expression. |
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| Keywords: | MCAO acupuncture RT-PCR NOS mRNA |
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