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31例老年人非何杰金淋巴瘤治疗分析
引用本文:张凤春,姜玉珍.31例老年人非何杰金淋巴瘤治疗分析[J].暨南大学学报,1998,19(6):79-80.
作者姓名:张凤春  姜玉珍
作者单位:白求恩医科大学第三临床学院血液肿瘤科
摘    要:对31例老年人(>60岁)非何杰金淋巴瘤临床治疗进行分析。治疗方案:CHOP(环磷酰胺、阿霉素、长春新硷及强的松)方案。将病人分为二组,A组:CHOP方案普通药物剂量组;B组:CHOP方案根据病人年龄及体质状态药物剂量减至A组的1/2~2/3。结果发现B组与A组完全缓解率基本一致,但是3年存活率明显高于A组,化疗相关残废率低于A组,化疗药物副作用亦低于A组。提示对老年人非何杰淋巴瘤适当减低化疗药物剂量,有利于提高疗效,保证生活质量,延长生存期

关 键 词:非何杰金淋巴瘤  治疗  老年人

Analysis of NHL Treated with CHOP in 31 Elderly Patients
Zhang Fengchun,Jiang Yuzhen Lin Yumei.Analysis of NHL Treated with CHOP in 31 Elderly Patients[J].Journal of Jinan University(Natural Science & Medicine Edition),1998,19(6):79-80.
Authors:Zhang Fengchun  Jiang Yuzhen Lin Yumei
Abstract:Objectvie:To explore a approach to treat Non-Hodgikkin lymphoma (NHL) with CHOP in 31 elderly patients. Methods: Chemotherapy regimen CHOP (CTX,ADM,VCR and Pred.)in group A:With general doses of CHOP,in group B:The doses were 1/2-2/3 of CHOP in group A . Result: Although the complete remission rate(CR)in group B was not higher than that in group A,the 3 years survival rate in goup B was significantly higher,and the side-effect and mortality of chemotherapy were lower than those in group A. Conclusion: An appropriate reduce of CHOP doses is favorable for improving efficiency of treatment,life quality of patients and lengthening survival time.KH 3mmD]
Keywords:NHL  chemotherapy  elderly  patients
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