| A novel theoretical model for mass transfer of hollow fiber hemodialyzers |
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| 引用本文： | DINGWeiping1,HE Liqun1,ZHAO Gang1,SHU Zhiquan1,CHENG Shuxia1 & GAO Dayong1,2 1. Department of Thermal Science & Energy Engineering,University of Science & Technology of China,Hefei 230027,China, 2. Department of Mechanical Engineering,University of Kentucky,Lexington,KY 40536-0108,USA Correspondence should be addressed to Gao Dayong (e-mail: dgao@engr. uky.edu). A novel theoretical model for mass transfer of hollow fiber hemodialyzers[J]. 科学通报(英文版), 2003, 48(21) |
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| 作者姓名： | DINGWeiping1 HE Liqun1 ZHAO Gang1 SHU Zhiquan1 CHENG Shuxia1 & GAO Dayong1 2 1. Department of Thermal Science & Energy Engineering University of Science & Technology of China Hefei 230027 China 2. Department of Mechanical Engineering University of Kentucky Lexington KY 40536-0108 USA Correspondence should be addressed to Gao Dayong (e-mail: dgao@engr. uky.edu) |
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| 作者单位： | Ding Weiping,He Liqun,ZHAO Gang,SHU Zhiquan,CHENG Shuxia(Department of Thermal Science & Energy Engineering, University of Science & Technology of China, Hefei 230027, China);GAO Dayong(Department of Thermal Science & Energy Engineering, University of Science & Technology of China, Hefei 230027, China;Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40536-0108, USA) |
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| 基金项目： | 中国科学院"百人计划" |
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| 摘 要： | Hemodialyzers have been applied to hemodialysiswidely. In order to get accurate mass transfer coefficient and clearance to determine treatment time, their masstransfer models have been studied deeply. The domesticstudy on hemodialyzers is later, focuses on experiment, and seldom refers to theoretical mechanism[1,2], but theoverseas research is more in-depth. Simple one-dimensional models have been used to simulate mass transfer in hemodialyzers by many re-searchers[3—7]. Their models assumed …
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A novel theoretical model for mass transfer of hollow fiber hemodialyzers |
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| Ding Weiping,He Liqun,ZHAO Gang,SHU Zhiquan,CHENG Shuxia,GAO Dayong. A novel theoretical model for mass transfer of hollow fiber hemodialyzers[J]. Chinese science bulletin, 2003, 48(21) |
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| Authors: | Ding Weiping He Liqun ZHAO Gang SHU Zhiquan CHENG Shuxia GAO Dayong |
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| Affiliation: | e-mail: dgao@engr. uky.edu |
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| Abstract: | A novel theoretical model for mass transfer of hollow fiber bundles in hemodialyzers is presented. In the model, a hemodialyzer is considered as a porous zone which is composed of two non-interpenetrating porous flow zones. Firstly, the dialysate side (shell side) is thought as a porous medium zone. Then by solidifying the dialysate flow zone and the occupied zone by hollow fiber membrane, the rest zone of hemodialyzer (i.e. blood side or lumen side) is con-sidered as a porous medium zone too. Finally, the interface of the two flow zones is the fiber membrane through which mass transfer is performed. The dialysate and blood flows are all described by Navier-Stokes equations with Darcy momentum source terms. Kedem-Katchalsky equations as other source terms are added into Navier-Stokes equations to simulate the permeating flux through the membrane. All equations must be coupled together in the process of com-puting. The model is validated by the experimental data in literature. The simulative results show that the predicted clearances agree well with the experimental data, and the model in this paper is better than other models for the fore-cast of clearance. |
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| Keywords: | porous media mass transfer hollow fiber clearance hemodialyzer. |
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