钙激活的大电导钾离子通道在成年斑胸草雀脑中的分布

BK 通道，即钙离子激活的大电导钾离子通道，它通过产生快速的后超极化（fA HP）来控制动作电位的持续时间、发放频率。为研究BK通道在鸣禽鸣唱学习中的作用提供形态学依据，用免疫组化法观察了BK通道在成年雄性斑胸草雀脑中的分布。证实了其在端脑、基底节纹状体、中脑、小脑等脑区都有广泛的表达，其中 RA、HVC、LM AN、X区、DM 等与鸣唱系统相关的核团都有显著的表达。这暗示了BK通道可能与鸣禽鸣唱信息整合、听觉反馈、鸣曲可塑性和稳定性以及呼吸调节都有密不可分的联系。

Ca2＋-activated K＋ channels of the BK-type in the brain of adult male zebra finches

BK channels ,large conductance calcium activated potassium channels ,w hich can generate fast after-hyperpolarization （fAHP） ,to control the duration and firing frequency of action potentials . To provide morphological basis for studying the role of BK channels in songbird vocal learning ,distri-bution of BK channels in the adult male zebra finches brain were observed with immunohistochemical method .The results showed that BK channels have a wide range of expression in the telencephalon , midbrain ,cerebellum ,basal ganglia striatum and other brain regions ,including RA ,HVC ,LM AN ,X , DM and other related song nuclei .The results suggested that BK channel may be related to voice in-formation integration ,auditory feedback ,song plasticity and stability as well as the regulation of res-piration .