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Increased silver stainability of metaphase chromosomes from rat hepatocytes during in vivo hepatocarcinogenesis |
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| Authors: | M Kirsch-Volders A Deleener M Lans J de Gerlache |
| Institution: | (1) Laboratory for Human Genetics, Free University of Brussels, Pleinlaan 2, B-1050 Brussels, (Belgium);(2) Unit of Biochemical Toxicology and Cancerology, University of Louvain, UCL 7369, B-1200 Brussels, (Belgium) |
| Abstract: | Summary Silver stainability of metaphase chromosomes was studied in hepatocytes obtained from rats exposed or not to a partial or complete carcinogenic treatment with diethylnitrosamine and phenobarbital. An increased hyperstaining is reported in the carcinogen-treated animals. |
| Keywords: | Silver strain hepatocyte chromosome carcinogen |
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