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均匀设计与逐步回归用于尿囊酸合成与优化
引用本文:肖敏,湛其亭.均匀设计与逐步回归用于尿囊酸合成与优化[J].吉首大学学报(自然科学版),1999,20(2):20-22.
作者姓名:肖敏  湛其亭
作者单位:[1]湖南大学化学化工系 [2]长沙电力学院化学系
基金项目:国家自然科学基金资助课题
摘    要:利用均匀实验设计逐步回归分析对三氯乙醛路线合成尿囊酸的条件进行了优化建模 ,找出了主次影响因素 ,获得了较好的合成产率及工艺条件。

关 键 词:合成计量学  均匀设计  逐步回归  尿囊酸

Homogeneous Design and Stepwise Regression as Used for Systematic Optimzation of Allantion Preparation
Xiao Min , Sheng Qiteng , Huang Ying Li Zhilinag.Homogeneous Design and Stepwise Regression as Used for Systematic Optimzation of Allantion Preparation[J].Journal of Jishou University(Natural Science Edition),1999,20(2):20-22.
Authors:Xiao Min  Sheng Qiteng [  ] Huang Ying Li Zhilinag
Institution:Xiao Min 1,2 Sheng Qiteng [1,3] Huang Ying 1Li Zhilinag 1
Abstract:Systematic invesigations were madde on synthometrics and its applications.Synthometrics was regarded as “Chemometrics in Synthetic Chemistry”or“Synthetic Chemometrics”.Uniform or homogeneous design (UD or HD) and stepwise regression (SR) were used,in this paper,for response modelling and synthesis optimization for preparation of allantion by the pothway of trichloroaldehyde (TCA).The primary factor was found to be reaction tempreature through experiments.The opfimal conditions for preparation of allantion were examined and the synthetic yield was obtained as well.
Keywords:synthometrics  chemometrics  homogeneous design  stepwise regression  allantion  systematic optimzation  synthetic chemometrics
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