Konfiguration und pharmakologische Aktivität bei 1-phenäthylsubstituierten 1,2,3,4-Tetrahydroisochinolinen |
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Authors: | A Rheiner Jr A Brossi |
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Institution: | (1) Chemische Forschungsabteilung der F. Hoffmann-La Roche & Co. AG, Basel, Schweiz |
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Abstract: | Summary The absolute configuration of four pharmacologically active tetrahydroisoquinolines has been determined. It was shown that both the levorotatory antipodes of I, II and III and the dextrorotatory enantiomer of IV possessR-configuration at the asymmetric center. |
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