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Effect of dipyridamole and adenosine monophosphate on cell proliferation in the hemopoietic tissue of normal and gamma-irradiated mice
Authors:M Pospí?il  M Hofer  J Netíková  ? Viklická  I Pipalová  A Bartoní?ková
Institution:(1) Institute of Biophysics, Czechoslovak Academy of Sciences, Královopolská 135, CS-61265 Brno, (Czechoslovakia)
Abstract:Combined treatment with dipyridamole and adenosine monophosphate enhances cell proliferation in the hemopoietic tissue of normal and gamma-irradiated mice. This effect can be explained by the elevation of extracellular adenosine, and the receptor-mediated activation of the cell adenylate cyclase system.
Keywords:Dipyridamole  adenosine monophosphate  cell proliferation  hemopoiesis  gamma-irradiation
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