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铜绿假单胞茵主动外排系统与耐药性关系的研究
引用本文:安乐,王艳艳,唐克,张晓天,王秀丽,刘月,李明成. 铜绿假单胞茵主动外排系统与耐药性关系的研究[J]. 北华大学学报(自然科学版), 2011, 12(1): 43-46
作者姓名:安乐  王艳艳  唐克  张晓天  王秀丽  刘月  李明成
作者单位:北华大学医学检验学院,吉林,吉林,132013
摘    要:铜绿假单胞菌是一种重要的院内感染条件致病菌,常感染癌症患者、烧伤患者等机体免疫力低下的患者,它对多种不同理化性质的药物高度耐药,其主动外排系统在耐药性中起主要作用.主要研究了铜绿假单胞菌主动外排泵的类型、组成及对抗生素耐药性的影响.

关 键 词:铜绿假单胞菌  主动外排系统  耐药性

On the Relationship of Active Efflux System in Pseudomonas aeruginosa and Its Drug Resistance
AN Le,WANG Yan-yan,TANG Ke,ZHANG Xiao-tian,WANG Xiu-li,LIU Yue,LI Ming-cheng. On the Relationship of Active Efflux System in Pseudomonas aeruginosa and Its Drug Resistance[J]. Journal of Beihua University(Natural Science), 2011, 12(1): 43-46
Authors:AN Le  WANG Yan-yan  TANG Ke  ZHANG Xiao-tian  WANG Xiu-li  LIU Yue  LI Ming-cheng
Affiliation:AN Le,WANG Yan-yan,TANG Ke,ZHANG Xiao-tian,WANG Xiu-li,LIU Yue,LI Ming-cheng(Medical Inspection College of Beihua University,Jilin 132013,China)
Abstract:Pseudomonas aeruginosa is a leading cause nosocomial infection,notably in immunocompromised patients such as cancer patients and burn patients.It shows highly drug resistance to drugs with different physical and chemical properties.The active efflux system play a principal role in the drug resistance.This paper summarizes the recent progress in the researches on the type and the composition of the active efflux pump,and the influence of it on the resistance of Pseudomonas aeruginosa to some antibiotics.
Keywords:Pseudomonas aeruginosa  active efflux system  drug resistance  
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