| 血液稀释对氯化铵中毒性肺水肿防治作用的实验研究 |
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| 引用本文： | 陈晴晖,陈少如,陈韩秋,许鸿举,张少民.血液稀释对氯化铵中毒性肺水肿防治作用的实验研究[J].汕头大学学报(自然科学版),1988(2). |
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| 作者姓名： | 陈晴晖 陈少如 陈韩秋 许鸿举 张少民 |
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| 作者单位： | 汕头大学医学院，汕头大学医学院，汕头大学医学院，汕头大学医学院，汕头大学医学院 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 本文以6%氯化铵(0.6ml/100g)腹腔注射造成大白鼠急性肺水肿模型,观察血液稀释对动物存活率及肺部形态学变化的影响.实验分为三组,氯化铵中毒组(中毒组,n=11),血液稀释(HD)预防组(HD 预防组,n=19)和血液稀释治疗组(HD 治疗组,n=10),结果表明,血液稀释可增加动物存活率(P<0.01),减轻肺部形态学改变,对氯化铵中毒性肺水肿有一定的预防和治疗作用.
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| 关 键 词： | 血液稀释 氯化铵 肺水肿 |
The Preventive and Therapeutic Effects of Hemodilution on Experimental Toxic Pulmonary Edema Induced by Ammonium Chloride in Rats |
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| Chen Qinghui Chen Shaoru Chen Hanqiu.The Preventive and Therapeutic Effects of Hemodilution on Experimental Toxic Pulmonary Edema Induced by Ammonium Chloride in Rats[J].Journal of Shantou University(Natural Science Edition),1988(2). |
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| Authors: | Chen Qinghui Chen Shaoru Chen Hanqiu |
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| Institution: | Shantou University Medical College |
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| Abstract: | Effects of hemodilution on the surviva rate and morphological changes of the lungs of animals were observed through the mode of acute pulmonary edema created by peritoneal injection of 6% Ammonium Chloride (0.6ml/100g) in rats.The animals were divided into three groups:the HD-preventive group (n= 19),the HD-treated group (n=10) and the control group(n=11).The experimental results showed that the morphologica changes of the HD-treated group and HD- preventive group were milder than those of the control group.The survival rate in the former two groups was significantly higher than that in the control group. The data suggest that hemodilution is effective in the prophylaxis and treatment of toxic pulmonary edema. |
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| Keywords: | Hemodilution Ammonium Ch oride Pulmonary edema |
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