| 急性长时间运动对大鼠心肌线粒体功能的影响 |
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| 引用本文： | 高彩暇. 急性长时间运动对大鼠心肌线粒体功能的影响[J]. 淮阴师范学院学报(自然科学版), 2009, 8(4): 337-340 |
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| 作者姓名： | 高彩暇 |
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| 作者单位： | 淮阴师范学院,体育学院,江苏,淮安,223300 |
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| 摘 要： | 探讨了急性长时间运动对大鼠心肌线粒体功能的影响.将8周龄大鼠雌性SD大鼠12只随机分成对照组(6只)和运动组(6只),运动组负重游泳299±29 min后立即处理取心肌线粒体测定线粒体RCR,线粒体抑制活性氧的能力以及[Ca2+]i.结果表明,一次性长时间运动后,大鼠心肌线粒体抑制活性氧(O2-.,OH)的能力下降(p<0.05),但线粒体呼吸功能完好(p>0.05),线粒体游离钙离子浓度没有发生变化(p>0.05).急性长时间运动产生的氧自由基还不足以攻击心肌线粒体.
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| 关 键 词： | 运动 心肌线粒体 呼吸控制率 活性氧 大鼠 动物实验 |
The Effects of Mitochondrial Function in Myocardiocytes After an Acute Bout of Strenuous Exercise in Rats |
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| GAO Cai-xia. The Effects of Mitochondrial Function in Myocardiocytes After an Acute Bout of Strenuous Exercise in Rats[J]. Journal of Huaiyin Teachers College(Natrual Science Edition), 2009, 8(4): 337-340 |
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| Authors: | GAO Cai-xia |
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| Abstract: | To study the effects of mitochondrial function in myocardio cytes after acute bout of strenuous exercise in rats.Methods: Put twelve 8-wee k s-old female SD rats randomly divide into contrast group(six) and exercise gro u p(six),then let the rads of exercise group swim with heavy swam 299±29 min av eragely,then killed to get myocardium mitochondria to measure mitochondria RCR,the ability of mitochondria's restrain to radical oxygen species(ROS) and i.Results: although the ability of rats' mitochondrial restrain to R eactive Oxygen Species(O·-2,OH)decreased(p<0.05),but rats' myocardium m itochondrial respiration controlling rate was complete(p>0.05),the concentrat i on of mitochondria free Ca2+was not changed(p>0.05) after an acute bout o f strenuous exercise.Conclusion: Produced ROS by an acute bout of strenuous exe rcise are't enough to attack myocardiocyte mitochondria. |
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| Keywords: | exercise cardiac muscle mitochondrial ribosome respiration controlling rate r eactive oxygen species rat: animal experiment |
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