The hypothalamic somatostatinergic pathways mediate feeding behavior in the rat |
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| Authors: | L T Ho Y F Chern M T Lin |
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| Institution: | Department of Internal Medicine, Veterans General Hospital, Taipei, Taiwan. |
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| Abstract: | The level of somatostatin in the hypothalamus was higher in satiated rats than in hungry rats. Elevating hypothalamic somatostatin levels by administering somatostatin into the hypothalamus produced a decrease in food intake, whereas lowering hypothalamic somatostatin levels by administering cysteamine into the peritoneal cavity produced an increase in food intake in rats. |
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