HLA groups in the infantile psychoses during development, and hypothesis for an enzyme defect] |
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Authors: | B Golse P Debray-Ritzen J Dausset M Lipinski J Hors |
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Abstract: | The HLA typing (loci A and B) of a series of fifteen psychotic children has shown an increase of the frequency of both HLA-A9 and B5 antigens. These preliminary data and previous biochemical findings in psychotic patients lead the authors to postulate the hypothesis of a qualitative or quantitative anomaly of the superoxide dismutase (SOD-2), the gene of which is situated on the same chromosome (sixth) as the HLA complex. |
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