| 溶解氧控制与发酵过程摄氧率及鸟苷积累的关系 |
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| 引用本文： | 刘咏梅,王仲石,王焕章,储炬,蔡显鹏,陈双喜. 溶解氧控制与发酵过程摄氧率及鸟苷积累的关系[J]. 华东理工大学学报(自然科学版), 2002, 28(3): 245-247 |
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| 作者姓名： | 刘咏梅 王仲石 王焕章 储炬 蔡显鹏 陈双喜 |
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| 作者单位： | 1. 星湖生物科技股份有限公司,广东,肇庆,526060
2. 华东理工大学生物反应器工程国家重点实验室,上海,200237 |
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| 基金项目： | 上海市曙光计划资助项目 ( 0 1 SG2 8) |
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| 摘 要： | 采用华东理工大学国家化工程技术研究中心（上海）生产的全自动多参数FUS－50L（A）生物反应器，在不同的控制方式下，研究了溶解氧水平对菌体代谢活力及鸟苷发酵水平的影响。结果表明：发酵过程中，用调节转速的方式控制发酵液中溶氧水平的效果比用空气流量好；发酵液中氧中溶氧水平控制在10％－20％时鸟苷积累量高，发酵液中溶氧水平低（5％）和高（30％）均不利于发酵液中的鸟苷积累。
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| 关 键 词： | 溶解氧 发酵 摄氧率 鸟苷积累 |
| 文章编号： | 1006-3080(2002)03-0245-03 |
| 修稿时间： | 2001-07-18 |
Relationship Between DO Level, OUR and Guanosine Accumulation in Guanosine Fermentation |
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| LIU Yong mei ,WANG Zhong shi ,WANG Huan zhang ,CHU Ju ,CAI Xian peng ,CHEN Shuang xi. Relationship Between DO Level, OUR and Guanosine Accumulation in Guanosine Fermentation[J]. Journal of East China University of Science and Technology, 2002, 28(3): 245-247 |
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| Authors: | LIU Yong mei WANG Zhong shi WANG Huan zhang CHU Ju CAI Xian peng CHEN Shuang xi |
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| Affiliation: | LIU Yong mei 1,WANG Zhong shi 1,WANG Huan zhang 1,CHU Ju 2*,CAI Xian peng 2,CHEN Shuang xi 2 |
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| Abstract: | By using the FUS 50L reactor produced by National Engineering Research Center For Biotechnology(Shanghai), the effect of dissolved oxygen( DO ) tension on guanosine accumulation in fermentation and the appropriate method for the control of DO were studied. The results show that for DO control and guanosine accumulation, adjusting the stirrer speed was better than adjusting the aeration rate and the DO controlled at 10%~20% was better than at 5% and 30%. |
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| Keywords: | fermentation guanosine dissolved oxygen oxygen uptake rate |
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